Are chrome flags safe to mess with?

the reset button only helps if chrome still opens. if a flag stops it from starting at all, close chrome, find the 'Local State' file in chrome's user data folder and rename it. the flags are stored there, so chrome starts with defaults again. rename it rather than delete, in case you want it back.

Low risk. Worst case Chrome gets glitchy or a page renders oddly. The flags page has a Reset all button at the top that puts everything back to default, then relaunch. The catch is they're experiments. Some get removed in a later update and a tip from a year ago may point at a flag that no longer exists, or that's now on by default anyway.